Cytokeratin 18 Protein (AA 2-423) (His tag)

Catalog No. ABIN1630372

Product Details

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Protein Type: Recombinant

Protein Characteristics: AA 2-423

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This Cytokeratin 18 protein is labelled with His tag.

Application: ELISA

Sequence: SFTTRSTTF STNYRSLGSV RTPSQRVRPA SSAASVYAGA GGSGSRISVS RSVWGGSVGS AGLAGMGGVQ TEKETMQDLN DRLASYLDKV KNLETENRRL ESKIREYLEK RGPQGVRDWG HYFKTIEDLR AQIFANSVDN ARIVLQIDNA RLAADDFRVK YETELAMRQS VESDIHGLRK VVDDTNITRL QLETEIEALK EELLFMKKNH EEEVQGLEAQ IASSGLTVEV DAPKSQDLSK IMADIRAQYE QLAQKNREEL DKYWSQQIEE STTVVTTKSA EIRDAETTLL ELRRTLQTLE IDLDSMKNQN INLENNLGEV EARYRVQMEQ LNGVLLHLES ELAQTRAEGQ RQTQEYEALL NIKVKLEAEI ATYRRLLEDG DDFSLNDALD SSNSMQTVQR TTTRKVVDGK VVSETNDTRV LRH

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Keratin, type I cytoskeletal 18 (Krt18) (KRT18 Products)

Synonyms: CK18 Protein, K18 Protein, Krt1-18 Protein, CYK18 Protein, DreK18 Protein, cb83 Protein, dapk1 Protein, sb:cb83 Protein, wu:fa13f02 Protein, wu:fb36b04 Protein, krt18 Protein, MGC64569 Protein, MGC75922 Protein, KRT18 Protein, CK-18-A Protein, K18-A Protein, NC-11 Protein, cyk18 Protein, k18 Protein, krt18-a Protein, krt18-b Protein, krt18a Protein, xkendob Protein, keratin 18 Protein, keratin 18, type I L homeolog Protein, keratin 18, type I Protein, keratin, type I cytoskeletal 18 Protein, K18, simple type I keratin Protein, Keratin, type I cytoskeletal 18 Protein, keratin 18, type I S homeolog Protein, Krt18 Protein, KRT18 Protein, krt18 Protein, krt18.L Protein, LOC700569 Protein, LOC100136778 Protein, k1c18 Protein, LOC100008885 Protein, krt18.S Protein

Background: Recommended name: Keratin, type I cytoskeletal 18.
Alternative name(s): Cytokeratin-18.
Short name= CK-18 Keratin-18.
Short name= K18

UniProt: Q5BJY9

Pathways: Apoptosis, Caspase Cascade in Apoptosis