SENP2 Protein (AA 363-589) (His tag,SUMO Tag)
SENP2
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- Target See all SENP2 Proteins
- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 363-589
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SENP2 protein is labelled with His tag,SUMO Tag.
- Purpose
- Recombinant Human Sentrin-Specific Protease 2/SENP2 (N-6His, SUMO tag)
- Sequence
- DDLLELTEDM EKEISNALGH GPQDEILSSA FKLRITRGDI QTLKNYHWLN DEVINFYMNL LVERNKKQGY PALHVFSTFF YPKLKSGGYQ AVKRWTKGVN LFEQEIILVP IHRKVHWSLV VIDLRKKCLK YLDSMGQKGH RICEILLQYL QDESKTKRNS DLNLLEWTHH SMKPHEIPQQ LNGSDCGMFT CKYADYISRD KPITFTQHQM PLFRKKMVWE ILHQQLL
- Characteristics
- Recombinant Human Sentrin-specific protease 2/SENP2 is produced with our E. coli expression system. The target protein is expressed with sequence (Asp363-Leu589) of Human SENP2 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES,5 % Glycerol, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
- Alternative Name
- SENP2 (SENP2 Products)
- Sub Type
- Fusionprotein
- Background
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SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2. - Molecular Weight
- 26.8 kDa
- UniProt
- Q9HC62
- Pathways
- Chromatin Binding
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