CD2 Protein (CD2) (AA 25-209) (His tag)

Catalog No. ABIN1880822

Product Details

Target: CD2

Protein Type: Recombinant

Protein Characteristics: AA 25-209

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CD2 protein is labelled with His tag.

Purpose: Recombinant Human LFA-3 Receptor/CD2 (C-6His)

Sequence: KEITNALETW GALGQDINLD IPSFQMSDDI DDIKWEKTSD KKKIAQFRKE KETFKEKDTY KLFKNGTLKI KHLKTDDQDI YKVSIYDTKG KNVLEKIFDL KIQERVSKPK ISWTCINTTL TCEVMNGTDP ELNLYQDGKH LKLSQRVITH KWTTSLSAKF KCTAGNKVSK ESSVEPVSCP EKGLDVDHHH HHH

Characteristics: Recombinant Human T-cell surface antigen CD2/CD2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys25-Asp209) of Human CD2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CD2

Alternative Name: T-Cell Surface Antigen CD2/CD2 (CD2 Products)

Sub Type: Fusionprotein

Background: T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5. It is a protein that in humans is encoded by the CD2 gene. It is a single-pass type I membrane protein. contains 1 Ig-like C2-type domain and 1 Ig-like V-type domain. T-cell surface antigen CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. It is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Alternative Names: T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5.

Molecular Weight: 22.5 kDa

UniProt: P06729