Disabled Homolog 1 (Drosophila) (DAB1) protein (Myc-DYKDDDDK Tag)

Details for Product No. ABIN2712270, Supplier: Log in to see
Protein Name
  • LOC100232823
  • si:dkey-242m13.1
  • DAB1
  • AI956902
  • C630028C02Rik
  • scm
  • scr
  • scrambler
  • yot
  • disabled-1
  • DAB1, reelin adaptor protein
  • disabled homolog 1
  • Dab, reelin signal transducer, homolog 1a (Drosophila)
  • disabled 1
  • DAB1
  • LOC100232823
  • dab1a
  • Dab1
Origin
Human
2
2
1
Source
HEK-293 Cells
2
1
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This DAB1 protein is labelled with Myc-DYKDDDDK Tag.
Application
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Options
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Specificity Optimal preservation of protein structure, post-translational modifications and functions.
Characteristics
  • Recombinant human DAB1 protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
Background The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Molecular Weight 59.8 kDa
NCBI Accession NP_066566
Application Notes Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Comment

The tag is located at the C-terminal.

Restrictions For Research Use only
Concentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Storage -80 °C
Storage Comment Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Supplier Images
Western Blotting (WB) image for Disabled Homolog 1 (Drosophila) (DAB1) protein (Myc-DYKDDDDK Tag) (ABIN2712270) Validation with Western Blot
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