TES Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712380

Product Details

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TES protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Testin / TES (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Alternative Name: Testin,tes (TES Products)

Synonyms: TESS Protein, TESS-2 Protein, tess Protein, tess-2 Protein, zgc:92091 Protein, xtes Protein, TES Protein, DKFZp469E2320 Protein, D6Ertd352e Protein, Tes1 Protein, Tes2 Protein, testin2 Protein, Testin Protein, testin LIM domain protein Protein, testin LIM domain protein L homeolog Protein, testis derived transcript (3 LIM domains) Protein, testis derived transcript Protein, TES Protein, tes.L Protein, tes Protein, Tes Protein

Background: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011].

Molecular Weight: 47.8 kDa

NCBI Accession: NP_056456