COX6C Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712467

Product Details

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This COX6C protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Complex IV subunit VIc protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Alternative Name: Complex IV Subunit Vic (COX6C Products)

Synonyms: COVIc Protein, COX-VIc Protein, Cox6c2 Protein, cox6c Protein, cox6ca Protein, cox6c.2 Protein, cox6cb Protein, GB30388 Protein, si:ch211-239j9.2 Protein, cytochrome c oxidase subunit 6C Protein, cytochrome c oxidase subunit VIc Protein, cytochrome c oxidase subunit VIc L homeolog Protein, cytochrome C oxidase subunit VIc Protein, COX6C protein Protein, COX6C Protein, Cox6c Protein, cox6c Protein, cox6c.1 Protein, cox6c.L Protein, IscW_ISCW016559 Protein, MGC148714 Protein

Background: Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77 % amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Molecular Weight: 8.6 kDa

NCBI Accession: NP_004365

Pathways: Proton Transport