CPT1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712538

Product Details

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CPT1A protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CPT1A / CPT1-L (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))

Alternative Name: Cpt1a,cpt1-L (CPT1A Products)

Synonyms: MGC53498 Protein, CPT1 Protein, CPT1-L Protein, L-CPT1 Protein, L-CPTI Protein, si:dkey-56p7.8 Protein, C730027G07 Protein, CPTI Protein, Cpt1 Protein, CPT-Ia Protein, carnitine palmitoyltransferase 1A (liver) L homeolog Protein, carnitine palmitoyltransferase 1A Protein, carnitine palmitoyltransferase 1A (liver) Protein, carnitine palmitoyltransferase 1Aa (liver) Protein, carnitine palmitoyltransferase 1a, liver Protein, cpt1a.L Protein, CPT1A Protein, cpt1a Protein, cpt1aa Protein, Cpt1a Protein

Background: The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 88.2 kDa

NCBI Accession: NP_001867

Pathways: AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process