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CRY1 Protein (Myc-DYKDDDDK Tag)

CRY1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2712572
  • Target See all CRY1 Proteins
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CRY1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Cryptochrome-1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CRY1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
    Alternative Name
    Cryptochrome-1 (CRY1 Products)
    Synonyms
    cry1-A Protein, CRY1 Protein, cry2 Protein, phll1 Protein, xCRY1 Protein, PHLL1 Protein, AU020726 Protein, AU021000 Protein, Phll1 Protein, ATCRY1 Protein, BLU1 Protein, BLUE LIGHT UNINHIBITED 1 Protein, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR Protein, ELONGATED HYPOCOTYL 4 Protein, HY4 Protein, OOP2 Protein, OUT OF PHASE 2 Protein, T3H13.14 Protein, T3H13_14 Protein, cryptochrome 1 Protein, cryptochrome circadian clock 1 L homeolog Protein, cryptochrome circadian regulator 1 Protein, cryptochrome circadian clock 1 Protein, Cryptochrome-1 Protein, cryptochrome 1 Protein, cryptochrome 1 (photolyase-like) Protein, cry1.L Protein, CRY1 Protein, cry1 Protein, siu50817b Protein, Cry1 Protein
    Background
    This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
    Molecular Weight
    66.2 kDa
    NCBI Accession
    NP_004066
    Pathways
    Response to Water Deprivation, Proton Transport
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