CRY1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712572

Product Details

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CRY1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Cryptochrome-1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Alternative Name: Cryptochrome-1 (CRY1 Products)

Synonyms: cry1-A Protein, CRY1 Protein, cry2 Protein, phll1 Protein, xCRY1 Protein, PHLL1 Protein, AU020726 Protein, AU021000 Protein, Phll1 Protein, ATCRY1 Protein, BLU1 Protein, BLUE LIGHT UNINHIBITED 1 Protein, CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR Protein, ELONGATED HYPOCOTYL 4 Protein, HY4 Protein, OOP2 Protein, OUT OF PHASE 2 Protein, T3H13.14 Protein, T3H13_14 Protein, cryptochrome 1 Protein, cryptochrome circadian clock 1 L homeolog Protein, cryptochrome circadian regulator 1 Protein, cryptochrome circadian clock 1 Protein, Cryptochrome-1 Protein, cryptochrome 1 Protein, cryptochrome 1 (photolyase-like) Protein, cry1.L Protein, CRY1 Protein, cry1 Protein, siu50817b Protein, Cry1 Protein

Background: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

Molecular Weight: 66.2 kDa

NCBI Accession: NP_004066

Pathways: Response to Water Deprivation, Proton Transport