CTBP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712600

Product Details

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CTBP1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CTBP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Boxer, Barajas, Tao, Zhang, Khavari: "ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes." in: Genes & development, Vol. 28, Issue 18, pp. 2013-26, (2014) (PubMed).

Target Details

Target: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Alternative Name: Ctbp1 (CTBP1 Products)

Synonyms: BARS Protein, CtBP1-L Protein, CtBP1-S Protein, CtBP3/BARS Protein, D4S115h Protein, D5H4S115 Protein, D5H4S115E Protein, 50-kDaBFA-inducedADP-ribosylatedsubstrate Protein, BARS-50 Protein, Bars Protein, wu:fi43a11 Protein, CtBP Protein, ctbp1-A Protein, xctbp1 Protein, bars Protein, CTBP1 Protein, C-terminal binding protein 1 Protein, C-terminal binding protein 1 L homeolog Protein, CTBP1 Protein, Ctbp1 Protein, ctbp1 Protein, ctbp1.L Protein

Background: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Molecular Weight: 47.4 kDa

NCBI Accession: NP_001319

Pathways: Retinoic Acid Receptor Signaling Pathway