PTGS1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712732

Product Details

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PTGS1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Cyclooxygenase 1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Alternative Name: Cyclooxygenase 1 (PTGS1 Products)

Synonyms: COX-1 Protein, cox-1 Protein, PTGS1 Protein, Ptgs1 Protein, COX1 Protein, Cox-1 Protein, Cox-3 Protein, PGHS-1 Protein, PHS 1 Protein, Pghs1 Protein, Cox1 Protein, Cox3 Protein, cox1 Protein, zCOX-1 Protein, COX3 Protein, PCOX1 Protein, PES-1 Protein, PGG/HS Protein, PGHS1 Protein, PHS1 Protein, PTGHS Protein, COX-3 Protein, prostaglandin-endoperoxide synthase 1 Protein, cyclooxygenase-1 Protein, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Protein, prostaglandin-endoperoxide synthase 1 S homeolog Protein, PTGS1 Protein, cox-1 Protein, Ptgs1 Protein, ptgs1 Protein, ptgs1.S Protein

Background: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells. [UniProtKB/Swiss-Prot Function]

Molecular Weight: 65.9 kDa

NCBI Accession: NP_000953