CYP2B6 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712763

Product Details

Target: CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CYP2B6 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CYP2B6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))

Alternative Name: Cyp2b6 (CYP2B6 Products)

Synonyms: CPB6 Protein, CYP2B Protein, CYP2B7 Protein, CYP2B7P Protein, CYPIIB6 Protein, EFVM Protein, IIB1 Protein, P450 Protein, CPF3 Protein, CYP4F Protein, LTB4H Protein, CYP2B30 Protein, CYP2B11 Protein, CYPIIB11 Protein, 21-OH Protein, 21OH Protein, 21OHA Protein, 21OHB Protein, CYP21OH-A Protein, Cyp21 Protein, Cyp21-ps1 Protein, Cyp21B Protein, Cyp21a2-ps Protein, Cyp21a2ps Protein, Oh21-1 Protein, Oh21-2 Protein, CYP2B6 Protein, cytochrome P450 family 2 subfamily B member 6 Protein, cytochrome P450 family 4 subfamily F member 3 Protein, cytochrome P450, family 2, subfamily B, polypeptide 6 Protein, cytochrome P450 family 2 subfamily B member 6 L homeolog Protein, cytochrome P450 2B11 Protein, cytochrome P450, family 21, subfamily a, polypeptide 1 Protein, cytochrome P450 subfamily 2B Protein, cytochrome P450 2B11-like Protein, CYP2B6 Protein, CYP4F3 Protein, cyp2b6.L Protein, Cyp21a1 Protein, LOC100068603 Protein

Background: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Molecular Weight: 56.1 kDa

NCBI Accession: NP_000758