CYP2E1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712770

Product Details

Target: CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CYP2E1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CYP2E1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Alternative Name: Cyp2e1 (CYP2E1 Products)

Synonyms: CYP2E1 Protein, CYP2E Protein, CYPIIE1 Protein, CPE1 Protein, P450-J Protein, P450C2E Protein, Cyp2e Protein, cytochrome P450, family 2, subfamily E, polypeptide 1 Protein, cytochrome P450 2E1 Protein, cytochrome P450 2E1-like Protein, cytochrome P450 family 2 subfamily E member 1 Protein, cytochrome P450, family 2, subfamily e, polypeptide 1 Protein, CYP2E1 Protein, PTRG_07411 Protein, LOC100342572 Protein, LOC100727914 Protein, LOC101843716 Protein, Cyp2e1 Protein

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Molecular Weight: 56.7 kDa

NCBI Accession: NP_000764