Cytohesin 2 Protein (CYTH2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712816

Product Details

Target: Cytohesin 2 (CYTH2)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Cytohesin 2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Cytohesin 2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Cytohesin 2 (CYTH2)

Alternative Name: Cytohesin 2 (CYTH2 Products)

Synonyms: ARNO Protein, CTS18 Protein, CTS18.1 Protein, PSCD2 Protein, PSCD2L Protein, SEC7L Protein, Sec7p-L Protein, Sec7p-like Protein, CLM2 Protein, Pscd2 Protein, Arno Protein, Sec7 Protein, Sec7B Protein, pscd2 Protein, MGC84366 Protein, CYTH2 Protein, cyth2 Protein, cytohesin 2 Protein, cytohesin-2 Protein, cytohesin 2 L homeolog Protein, si:dkey-283b15.4 Protein, CYTH2 Protein, PTRG_08834 Protein, Cyth2 Protein, cyth2.L Protein, cyth2 Protein, si:dkey-283b15.4 Protein

Background: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83 % homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 46.4 kDa

NCBI Accession: NP_059431