CLNK Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712837

Product Details

Target: CLNK (Cytokine-Dependent Hematopoietic Cell Linker (CLNK))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CLNK protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CLNK / MIST protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CLNK (Cytokine-Dependent Hematopoietic Cell Linker (CLNK))

Abstract: CLNK Products

Synonyms: MIST Protein, Mist Protein, RGD1562417 Protein, cytokine dependent hematopoietic cell linker Protein, cytokine-dependent hematopoietic cell linker Protein, CLNK Protein, Clnk Protein

Background: MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603 BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1 MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326] Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]

Molecular Weight: 49.4 kDa

NCBI Accession: NP_443196