AKTIP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all AKTIP Proteins
- AKTIP (AKT Interacting Protein (AKTIP))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AKTIP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human AKTIP / FTS (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product AKTIP Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- AKTIP (AKT Interacting Protein (AKTIP))
- Alternative Name
- Aktip,fts (AKTIP Products)
- Synonyms
- FT1 Protein, FTS Protein, cb798 Protein, fts Protein, zgc:77699 Protein, fts-A Protein, aktip Protein, fts-B Protein, MGC133931 Protein, AL023020 Protein, Fif Protein, Ft Protein, Ft1 Protein, Fts Protein, AKT interacting protein Protein, akt interacting protein Protein, AKT interacting protein L homeolog Protein, AKT interacting protein S homeolog Protein, thymoma viral proto-oncogene 1 interacting protein Protein, AKTIP Protein, aktip Protein, aktip.L Protein, aktip.S Protein, Aktip Protein
- Background
- The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
- Molecular Weight
- 32.9 kDa
- NCBI Accession
- NP_071921
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