Bardet-Biedl Syndrome 7 (BBS7) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Details for Product No. ABIN2715168
Protein Name
  • BBS7
  • bbs2l1
  • BBS2L1
  • id:ibd5048
  • zgc:153772
  • 8430406N16Rik
  • Bardet-Biedl syndrome 7
  • bardet-biedl syndrome 7
  • Bardet-Biedl syndrome 7 L homeolog
  • Bardet-Biedl syndrome 7 (human)
  • BBS7
  • bbs7
  • MICPUN_100192
  • MICPUCDRAFT_16331
  • bbs7.L
  • Bbs7
Protein Characteristics
Transcript Variant 2
3
1
Origin
Human
3
1
Source
HEK-293 Cells
2
2
Protein Type
Recombinant
Purification tag / Conjugate
This BBS7 protein is labelled with Myc-DYKDDDDK Tag.
Application
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Options
Specificity Optimal preservation of protein structure, post-translational modifications and functions.
Characteristics
  • Recombinant human BBS7 (transcript variant 2) protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein Name
Background This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014].
Molecular Weight 75.3 kDa
NCBI Accession NP_060660
Pathways Hedgehog Signaling
Application Notes Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Comment

The tag is located at the C-terminal.

Restrictions For Research Use only
Concentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Storage -80 °C
Storage Comment Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Supplier Images
Image no. 1 for Bardet-Biedl Syndrome 7 (BBS7) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) (ABIN2715168) Validation with Western Blot
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