BBS7 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2715168

Product Details

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BBS7 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human BBS7 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Alternative Name: Bbs7 (BBS7 Products)

Synonyms: BBS7 Protein, bbs2l1 Protein, BBS2L1 Protein, id:ibd5048 Protein, zgc:153772 Protein, 8430406N16Rik Protein, Bardet-Biedl syndrome 7 Protein, bardet-biedl syndrome 7 Protein, Bardet-Biedl syndrome 7 L homeolog Protein, Bardet-Biedl syndrome 7 (human) Protein, BBS7 Protein, bbs7 Protein, MICPUN_100192 Protein, MICPUCDRAFT_16331 Protein, bbs7.L Protein, Bbs7 Protein

Background: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014].

Molecular Weight: 75.3 kDa

NCBI Accession: NP_060660

Pathways: Hedgehog Signaling