Nardilysin (N-Arginine Dibasic Convertase) (NRD1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Details for Product No. ABIN2726830
Protein Name
Protein Characteristics
Transcript Variant 1
1
1
1
Origin
Human
2
1
Source
HEK-293 Cells
2
1
Protein Type
Recombinant
Purification tag / Conjugate
This NRD1 protein is labelled with Myc-DYKDDDDK Tag.
Application
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Options
Specificity Optimal preservation of protein structure, post-translational modifications and functions.
Characteristics
  • Recombinant human Nardilysin (transcript variant 1) protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein Name
Background This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 139.2 kDa
NCBI Accession NP_002516
Pathways Skeletal Muscle Fiber Development
Application Notes Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Comment

The tag is located at the C-terminal.

Restrictions For Research Use only
Concentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Storage -80 °C
Storage Comment Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Supplier Images
Image no. 1 for Nardilysin (N-Arginine Dibasic Convertase) (NRD1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) (ABIN2726830) Validation with Western Blot