NSL1 Protein (His tag)

Catalog No. ABIN2727644

Product Details

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NSL1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NSL1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NSL1 (NSL1, MIND Kinetochore Complex Component, Homolog (NSL1))

Alternative Name: Nsl1 (NSL1 Products)

Synonyms: 4833432M17Rik Protein, AI451597 Protein, Gm105 Protein, Gm984 Protein, C1orf48 Protein, MIS14 Protein, NSL1, MIS12 kinetochore complex component Protein, NSL1, MIS12 kinetochore complex component L homeolog Protein, NSL1 Protein, nsl1.L Protein, nsl1 Protein, Nsl1 Protein

Background: This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3&apos UTR region of this gene on chromosome X.

Molecular Weight: 32 kDa

NCBI Accession: NP_056286