LCP1 Protein (Myc-DYKDDDDK Tag)
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- Target See all LCP1 Proteins
- LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LCP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Plastin 2 / LCP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions." in: Free radical biology & medicine, Vol. 86, pp. 1-15, (2015) (PubMed).
: "
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L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions." in: Free radical biology & medicine, Vol. 86, pp. 1-15, (2015) (PubMed).
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- Target
- LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))
- Alternative Name
- Plastin 2,lcp1 (LCP1 Products)
- Synonyms
- CP64 Protein, L-PLASTIN Protein, LC64P Protein, LPL Protein, PLS2 Protein, cb245 Protein, fj24b12 Protein, wu:fj24b12 Protein, cp64 Protein, l-plastin Protein, lc64p Protein, lpl Protein, pls2 Protein, plastin-2 Protein, AW536232 Protein, D14Ertd310e Protein, LCP-1 Protein, Pls2 Protein, pp65 Protein, lymphocyte cytosolic protein 1 Protein, lymphocyte cytosolic protein 1 (L-plastin) Protein, lymphocyte cytosolic protein 1 (L-plastin) S homeolog Protein, lower matrix protein; involved in immune regulation Protein, LCP1 Protein, lcp1 Protein, lcp1.S Protein, Lcp1 Protein, UL83 Protein
- Background
- Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
- Molecular Weight
- 70.1 kDa
- NCBI Accession
- NP_002289
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