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Protein Phosphatase 1, Regulatory Subunit 16A (PPP1R16A) protein (Myc-DYKDDDDK Tag) Protein

PPP1R16A Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2729476
$888.80
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20 μg
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  • Protein Name
    Protein Type
    Recombinant
    Origin
    Human
    Source
    HEK-293 Cells
    Purification tag / Conjugate
    Myc-DYKDDDDK Tag
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificity
    Optimal preservation of protein structure, post-translational modifications and functions.
    Characteristics
    • Recombinant human PPP1R16A / MYPT3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Protein Name
    Synonyms
    2900084E10Rik, Mypt3, R75527, MYPT3, protein phosphatase 1, regulatory (inhibitor) subunit 16A, protein phosphatase 1 regulatory subunit 16A, protein phosphatase 1, regulatory subunit 16A, Ppp1r16a, PPP1R16A
    Background
    Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.
    Molecular Weight
    57.6 kDa
    NCBI Accession
    NP_116291
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