TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein
TIA1 Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2733699
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- Protein Name
- Protein Type
- Protein Characteristics
- Transcript Variant 2
- HEK-293 Cells
- Purification tag / Conjugate
- This TIA1 protein is labelled with Myc-DYKDDDDK Tag.
- Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
- Optimal preservation of protein structure, post-translational modifications and functions.
- Recombinant human TIA1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Application Notes
- Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
In vitro biochemical assays and cell-based functional assays
The tag is located at the C-terminal.
- For Research Use only
- > 50 μg/mL
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
- Protein Name
- The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
- Molecular Weight
- 42.8 kDa
- NCBI Accession
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