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TIA1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

TIA1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733699
  • Target See all TIA1 Proteins
    TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 7
    • 3
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TIA1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TIA1 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product TIA1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
    Alternative Name
    Tia1 (TIA1 Products)
    Background
    The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
    Molecular Weight
    42.8 kDa
    NCBI Accession
    NP_071505
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