TYROBP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
TYROBP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- Target See all TYROBP Proteins
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TYROBP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TYROBP / DAP12 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TYROBP Protein
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TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 1-113) protein (GST tag)
TYROBP Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA
TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 21-113) protein (GST tag)TYROBP Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
- Alternative Name
- Tyrobp,dap12 (TYROBP Products)
- Background
- This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
- Molecular Weight
- 9.3 kDa
- NCBI Accession
- NP_003323
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