Exportin 2 Protein (Myc-DYKDDDDK Tag)
CSE1L
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all Exportin 2 (CSE1L) Proteins
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Exportin 2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human XPO2 / Exportin-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CSE1L Protein
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CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 872-971) protein (GST tag)
CSE1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 1-195) protein (GST tag)CSE1L Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
- Alternative Name
- Xpo2,exportin-2 (CSE1L Products)
- Background
- Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 110.2 kDa
- NCBI Accession
- NP_001307
- Pathways
- Protein targeting to Nucleus
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