Vaccinia Virus B18R (VACV B18R) (AA 20-351) (Active) protein (His tag)
VACV B18R
Origin: Vaccinia Virus (VACV)
Host: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
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- Target
- Vaccinia Virus B18R (VACV B18R)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 20-351
- Origin
- Vaccinia Virus (VACV)
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- His tag
- Sequence
- AA 20-351
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Vaccinia Virus B18R (VACV B18R) protein (His tag)
VACV B18R Origin: Vaccinia Virus (VACV) Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- Vaccinia Virus B18R (VACV B18R)
- Alternative Name
- B18R
- Target Type
- Viral Protein
- Background
- B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
- Molecular Weight
- 40.3 kDa
- UniProt
- P25213
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