ICAM2 Protein (AA 25-223) (His tag)
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- Target See all ICAM2 Proteins
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-223
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ICAM2 protein is labelled with His tag.
- Purpose
- Recombinant Human Intercellular Adhesion Molecule 2/ICAM-2/CD102 (C-6His)
- Sequence
- KVFEVHVRPK KLAVEPKGSL EVNCSTTCNQ PEVGGLETSL DKILLDEQAQ WKHYLVSNIS HDTVLQCHFT CSGKQESMNS NVSVYQPPRQ VILTLQPTLV AVGKSFTIEC RVPTVEPLDS LTLFLFRGNE TLHYETFGKA APAPQEATAT FNSTADREDG HRNFSCLAVL DLMSRGGNIF HKHSAPKMLE IYEPVSDSQV DHHHHHH
- Characteristics
- Recombinant Human Intercellular Adhesion Molecule 2/ICAM-2 produced by transfected human cells is a secreted protein with sequence (Lys25-Gln223) of Human ICAM2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ICAM2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 2 mM CaCl2, 2 mM MgCl2, 5 % Threhalose, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
- Alternative Name
- cd102 (ICAM2 Products)
- Synonyms
- ICAM2 Protein, CD102 Protein, Icam-2 Protein, Ly-60 Protein, intercellular adhesion molecule 2 Protein, LOC506088 Protein, ICAM2 Protein, LOC616254 Protein, LOC100140873 Protein, Icam2 Protein
- Sub Type
- Fusionprotein
- Background
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ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Alternative Names: Intercellular Adhesion Molecule 2, ICAM-2, CD102, ICAM2 - Molecular Weight
- 23.13 kDa
- UniProt
- P13598
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