CFHR2 Protein (AA 19-270) (His tag)

Catalog No. ABIN4370401

Product Details

Target: CFHR2 (Complement Factor H-Related 2 (CFHR2))

Protein Type: Recombinant

Protein Characteristics: AA 19-270

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CFHR2 protein is labelled with His tag.

Purpose: Recombinant Human Complement Factor H-Related Protein 2/CFHR2 (C-6His)

Sequence: EAMFCDFPKI NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCAEEGWS PTPKCLRLCF FPFVENGHSE SSGQTHLEGD TVQIICNTGY RLQNNENNIS CVERGWSTPP KCRSTISAEK CGPPPPIDNG DITSFLLSVY APGSSVEYQC QNLYQLEGNN QITCRNGQWS EPPKCLDPCV ISQEIMEKYN IKLKWTNQQK LYSRTGDIVE FVCKSGYHPT KSHSFRAMCQ NGKLVYPSCE EKVDHHHHHH

Characteristics: Recombinant Human Complement Factor H-Related Protein 2/CFHR2 produced by transfected human cells is a secreted protein with sequence (Glu19-Lys270) of human CFHR2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CFHR2 (Complement Factor H-Related 2 (CFHR2))

Alternative Name: complement-factor-h-related-2 (CFHR2 Products)

Sub Type: Fusionprotein

Background: Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.
Alternative Names: Complement Factor H-Related Protein 2, FHR-2, DDESK59, H Factor-Like 3, H Factor-Like Protein 2, CFHR2, CFHL2, FHR2, HFL3

Molecular Weight: 29.78 kDa

UniProt: P36980