Anaphase Promoting Complex Subunit 15 (ANAPC15) (AA 1-121), (full length) protein (GST tag) Protein
ANAPC15
Origin: Human
Source: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
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Catalog No. ABIN5709159
$456.50
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100 μg ABIN5709159
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- Protein Name
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-121
- Origin
- Human
- Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- GST tag
- Application
- SDS-PAGE (SDS)
- Sequence
- MSTLFPSLFP RVTETLWFNL DRPCVEETEL QQQEQQHQAW LQSIAEKDNN LVPIGKPASE HYDDEEEEDD EDDEDSEEDS EDDEDMQDMD EMNDYNESPD DGEVNEVDME GNEQDQDQWM I
- Purification
- SDS-PAGE
- Purity
- > 90 %
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- Protein Name
- Background
- Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assbly checkpoint. Also required for degradation of CDC20.
- Molecular Weight
- 41.7 kDa
- UniProt
- P60006
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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