SUPT16H Protein (AA 890-1074, partial) (His-SUMO Tag)

Catalog No. ABIN5710442

Product Details

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Protein Type: Recombinant

Protein Characteristics: AA 890-1074, partial

Origin: Arabidopsis thaliana

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SUPT16H protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: DFKKDVLRVD SVPTSSLEGI KEWLDTTDIK YYESKLNLNW RQILKTITDD PQSFIDDGGW EFLNLDGSDS ESGGSEESDK GYEPSDVEVE SESEDEASES ESLVESDDDE EEDSEQESEE EKGKTWDELE REATNADREH GVESDSEEER KRRKMKAFGK SRPGTSGGGG SSSMKNMPPS KRKHR

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Alternative Name: SPT16 (SUPT16H Products)

Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a tplate such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable).

Molecular Weight: 36.89 kDa

UniProt: O82491

Pathways: Chromatin Binding