Murinoglobulin 1 Protein (Mug1) (AA 700-910, partial) (His tag)
Mug1
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Target See all Murinoglobulin 1 (Mug1) products
- Murinoglobulin 1 (Mug1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 700-910, partial
- Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Murinoglobulin 1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- TPEISWSLRT TLSKRPEEPP RKDPSSNDPL TETIRKYFPE TWVWDIVTVN STGLAEVEMT VPDTITEWKA GALCLSNDTG LGLSSVVPLQ AFKPFFVEVS LPYSVVRGEA FMLKATVMNY LPTSMQMSVQ LEASPDFTAV PVGDDQDSYC LSANGRHTSS WLVTPKSLGN VNFSVSAEAQ QSSEPCGSEV ATVPETGRKD TVVKVLIVEP E
- Purification
- SDS-PAGE
- Purity
- > 90 %
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Murinoglobulin 1 (Mug1) (AA 28-1476) protein (His tag)
Crystallography grade Mug1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Murinoglobulin 1 (Mug1)
- Alternative Name
- MUG1 (Mug1 Products)
- Synonyms
- murinoglobulin 1 Protein, Mug1 Protein
- Background
- A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.
- Molecular Weight
- 27.13 kDa
- UniProt
- P28665
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