14-3-3 eta Protein (YWHAH) (AA 4-246, partial) (GST tag)

Catalog No. ABIN5712211

Product Details

Target: 14-3-3 eta (YWHAH)

Protein Type: Recombinant

Protein Characteristics: AA 4-246, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This 14-3-3 eta protein is labelled with GST tag.

Application: SDS-PAGE (SDS)

Sequence: REQLLQRARL AEQAERYDDM ASAMKAVTEL NEPLSNEDRN LLSVAYKNVV GARRSSWRVI SSIEQKTMAD GNEKKLEKVK AYREKIEKEL ETVCNDVLSL LDKFLIKNCN DFQYESKVFY LKMKGDYYRY LAEVASGEKK NSVVEASEAA YKEAFEISKE QMQPTHPIRL GLALNFSVFY YEIQNAPEQA CLLAKQAFDD AIAELDTLNE DSYKDSTLIM QLLRDNLTLW TSDQQDEEAG EGN

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: 14-3-3 eta (YWHAH)

Alternative Name: 1433F (YWHAH Products)

Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Molecular Weight: 55.3 kDa

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction