HDAC4 Protein (AA 1-227, partial) (GST tag)
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- Target See all HDAC4 Proteins
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-227, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HDAC4 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPSAVPMD LRLDHQFSLP VAEPALREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQQEMLA MKHQQELLEH QRKLERHRQE QELEKQHREQ KLQQLKNKEK GKESAVASTE VKMKLQEFVL NKKKALAHRN LNHCISSDPR YWYGKTQHSS LDQSSPPQSG VSTSYNH
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HDAC4 Protein
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Histone Deacetylase 4 (HDAC4) (AA 1-1084) protein (His tag)
custom-made HDAC4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Histone Deacetylase 4 (HDAC4) (AA 1-1076) protein (His tag)custom-made HDAC4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Histone Deacetylase 4 (HDAC4) (AA 1-972) protein (GST tag)HDAC4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Histone Deacetylase 4 (HDAC4) (AA 551-648) protein (GST tag)HDAC4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Histone Deacetylase 4 (HDAC4) protein (Myc-DYKDDDDK Tag)HDAC4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Alternative Name
- HDAC4 (HDAC4 Products)
- Background
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
- Molecular Weight
- 53.7 kDa
- UniProt
- P56524
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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