CK1 epsilon Protein (AA 1-416, full length) (His tag)
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- Target See all CK1 epsilon (CSNK1E) Proteins
- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-416
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This CK1 epsilon protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MELRVGNKYR LGRKIGSGSF GDIYLGANIA SGEEVAIKLE CVKTKHPQLH IESKFYKMMQ GGVGIPSIKW CGAEGDYNVM VMELLGPSLE DLFNFCSRKF SLKTVLLLAD QMISRIEYIH SKNFIHRDVK PDNFLMGLGK KGNLVYIIDF GLAKKYRDAR THQHIPYREN KNLTGTARYA SINTHLGIEQ SRRDDLESLG YVLMYFNLGS LPWQGLKAAT KRQKYERISE KKMSTPIEVL CKGYPSEFST YLNFCRSLRF DDKPDYSYLR QLFRNLFHRQ GFSYDYVFDW NMLKFGAARN PEDVDRERRE HEREERMGQL RGSATRALPP GPPTGATANR LRSAAEPVAS TPASRIQPAG NTSPRAISRV DRERKVSMRL HRGAPANVSS SDLTGRQEVS RIPASQTSVP FDHLGK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CSNK1E Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
- Alternative Name
- KC1E (CSNK1E Products)
- Background
- Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
- Molecular Weight
- 49.3 kDa
- UniProt
- P49674
- Pathways
- Hedgehog Signaling, M Phase
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