CD51 Protein (AA 891-1048) (His tag)

Catalog No. ABIN5713570

Product Details

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Protein Type: Recombinant

Protein Characteristics: AA 891-1048

Origin: Human

Source: Yeast

Purification tag / Conjugate: This CD51 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: DLALSEGDIH TLGCGVAQCL KIVCQVGRLD RGKSAILYVK SLLWTETFMN KENQNHSYSL KSSASFNVIE FPYKNLPIED ITNSTLVTTN VTWGIQPAPM PVPVWVIILA VLAGLLLLAV LVFVMYRMGF FKRVRPPQEE QEREQLQPHE NGEGNSET

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: ITAV (ITGAV Products)

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein ses to enhance angiogenesis in Kaposi's sarcoma lesions.

Molecular Weight: 19.7 kDa

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex