METRNL Protein (AA 46-311) (His tag)
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- Target See all METRNL Proteins
- METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 46-311
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This METRNL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- QYSSDRCSWK GSGLTHEAHR KEVEQVYLRC AAGAVEWMYP TGALIVNLRP NTFSPARHLT VCIRSFTDSS GANIYLEKTG ELRLLVPDGD GRPGRVQCFG LEQGGLFVEA TPQQDIGRRT TGFQYELVRR HRASDLHELS APCRPCSDTE VLLAVCTSDF AVRGSIQQVT HEPERQDSAI HLRVSRLYRQ KSRVFEPVPE GDGHWQGRVR TLLECGVRPG HGDFLFTGHM HFGEARLGCA PRFKDFQRMY RDAQERGLNP CEVGTD
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product METRNL Protein
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Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (AA 46-311) protein (His-IF2DI Tag)
METRNL Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Meteorin, Glial Cell Differentiation Regulator-Like (METRNL) (AA 46-311) protein (His tag)METRNL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- METRNL (Meteorin, Glial Cell Differentiation Regulator-Like (METRNL))
- Alternative Name
- METRL (METRNL Products)
- Background
- Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold tperatures .
- Molecular Weight
- 31.96 kDa
- UniProt
- Q641Q3
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