Prohibitin 2 Protein (PHB2) (AA 1-299) (His tag)
PHB2
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 85 % by SDS - PAGE
SDS
1 image
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- Target See all Prohibitin 2 (PHB2) Proteins
- Prohibitin 2 (PHB2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-299
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Prohibitin 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAQNLKD LAGRLPAGPR GMGTALKLLL GAGAVAYGVR ESVFTVEGGH RAIFFNRIGG VQQDTILAEG LHFRIPWFQY PIIYDIRARP RKISSPTGSK DLQMVNISLR VLSRPNAQEL PSMYQRLGLD YEERVLPSIV NEVLKSVVAK FNASQLITQR AQVSLLIRRE LTERAKDFSL ILDDVAITEL SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PHB2 Protein
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Prohibitin 2 (PHB2) (AA 37-299) protein (GST tag)
PHB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Prohibitin 2 (PHB2) (AA 1-299) protein (GST tag)PHB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- Prohibitin 2 (PHB2)
- Alternative Name
- PHB2 (PHB2 Products)
- Background
- PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. Recombinant human PHB2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 35.7 kDa (322aa)
- NCBI Accession
- NP_001138303
- UniProt
- Q99623
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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