Caspase 2 Protein (AA 348-452) (His tag)
-
- Target See all Caspase 2 (CASP2) Proteins
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 348-452
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Caspase 2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MAGKEKLPKM RLPTRSDMIC GYACLKGTAA MRNTKRGSWY IEALAQVFSE RACDMHVADM LVKVNALIKD REGYAPGTEF HRCKEMSEYC STLCRHLYLF PGHPPT
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product CASP2 Protein
-
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 121-220) protein (GST tag)
CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 1-452) protein (GST tag)CASP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (AA 2-452) protein (His-SUMO Tag)CASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (Active) proteinCASP2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Active
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Denatured
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Alternative Name
- CASP2 (CASP2 Products)
- Background
- CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. Recombinant human CASP2 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 14.1kDa (126aa)
- NCBI Accession
- NP_116764
- UniProt
- P42575
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
-
