BMP7 Protein (AA 292-430) (His tag)
BMP7
Origin: Mouse
Host: Escherichia coli (E. coli)
> 97 %
AcA, CC
Active
2 images
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- Target See all BMP7 Proteins
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Biological Activity
- Active
- Protein Characteristics
- AA 292-430
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This BMP7 protein is labelled with His tag.
- Application
- Activity Assay (AcA), Cell Culture (CC)
- Characteristics
- Tag location: N-terminal His Tag
- Purity
- > 97 %
- Biological Activity Comment
- BMP7 (Bone morphogenetic protein 7), which belongs to the TGF-β superfamily, is a signaling molecule with the ability to promote bone formation. BMP7 has also been implicated in various types of cancer, including breast cancer. It has been reported that BMP7 treatment induced cell growth promotion of MDA-MB-231 breast cancer line. To test the effect of BMP7 on cell proliferation, MDA-MB-231 cells were seeded into triplicate wells of 96-well plates at a density of 2,000 cells/well and allowed to attach overnight, then the medium was replaced with serum-free standard DMEM prior to the addition of various concentrations of BMP7. After incubated for 72h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10μL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37°C.
- Top Product
- Discover our top product BMP7 Protein
-
Bone Morphogenetic Protein 7 (BMP7) (AA 1-431) protein (GST tag)
BMP7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Isoelectric Point: 8.5
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.
- Preservative
- Dithiothreitol (DTT), Other preservative, ProClin
- Precaution of Use
- This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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- Target
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Abstract
- BMP7 Products
- Background
- Alternative Names: OP1, Osteogenic Protein-1, Eptotermin alfa
- Molecular Weight
- 16.9kDa
- UniProt
- P23359
- Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
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