GZMH Protein (AA 19-246) (His tag)
-
- Target See all GZMH Proteins
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-246
- Origin
- Human
-
Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This GZMH protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- EEIIGGHEAK PHSRPYMAFV QFLQEKSRKR CGGILVRKDF VLTAAHCQGS SINVTLGAHN IKEQERTQQF IPVKRPIPHP AYNPKNFSND IMLLQLERKA KWTTAVRPLR LPSSKAQVKP GQLCSVAGWG YVSMSTLATT LQEVLLTVQK DCQCERLFHG NYSRATEICV GDPKKTQTGF KGDSGGPLVC KDVAQGILSY GNKKGTPPGV YIKVSHFLPW IKRTMKRLHH HHHH
- Purity
- > 90 % by SDS - PAGE
- Endotoxin Level
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product GZMH Protein
-
Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 1-246) protein (GST tag)
GZMH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 147-246) protein (GST tag)GZMH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 161-246) protein (GST tag)GZMH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 21-246) protein (His tag)Crystallography grade GZMH Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- Target
- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
- Alternative Name
- GZMH (GZMH Products)
- Synonyms
- GZMH Protein, CCP-X Protein, CGL-2 Protein, CSP-C Protein, CTLA1 Protein, CTSGL2 Protein, granzyme H Protein, LOC617313 Protein, GZMH Protein
- Background
- GZMH, as known as granzyme H isoform 1, is a member of the granzyme family of serine proteases found specifically in the granules of cytotoxic Tlymphocytes (CTL) and natural killer (NK) cells. The more abundant expression of this protein than granzyme B in NK cells suggests that granzyme H may complement the pro-apoptotic function of granzyme B in this cell type. Recombinant human GZMH, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Molecular Weight
- 26.2kDa (234aa) 28-40kDa (SDS-PAGE under reducing conditions)
- NCBI Accession
- NP_219491
- UniProt
- P20718
-
