DCXR Protein (AA 1-244) (His tag)
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- Target See all DCXR Proteins
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 1-244
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCXR protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
- Purity
- > 95 % by SDS - PAGE
- Biological Activity Comment
- Specific activity is > 1,800 pmol/min/ug and is defined as the amount of enzyme that oxidize 1pmole of xylitol to L-xylulose per minute at pH 10.0 at 37C.
- Top Product
- Discover our top product DCXR Protein
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Dicarbonyl/L-Xylulose Reductase (DCXR) (AA 1-244) protein (His tag)
custom-made DCXR Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dicarbonyl/L-Xylulose Reductase (DCXR) (AA 1-244) protein (His tag)DCXR Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Dicarbonyl/L-Xylulose Reductase (DCXR) (AA 1-244) protein (GST tag)DCXR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Dicarbonyl/L-Xylulose Reductase (DCXR) (AA 1-244) protein (His tag)custom-made DCXR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Dicarbonyl/L-Xylulose Reductase (DCXR) (Transcript Variant 2) protein (His tag)DCXR Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dicarbonyl/L-Xylulose Reductase (DCXR) protein (Myc-DYKDDDDK Tag)DCXR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Bioactivity Validated
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 1 mM DTT, 20 % glycerol, 50 mM NaCl
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))
- Alternative Name
- DCXR (DCXR Products)
- Background
- Dicarbonyl/L-xylulose reductase, also known as DCXR, is an enzyme responsible for the metabolism of xylulose, converting it into xylitol. DCXR was expressed at low levels and was localized predominantly in the cytoplasmic membrane. In contrast, in virtually all grades of early-stage prostate cancer and in all chemohormonally treated cases, DCXR was strikingly overexpressed and was localized predominantly in the cytoplasm and nucleus. Recombinant human DCXR, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 28 kDa (264aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_057370
- UniProt
- Q7Z4W1
- Pathways
- Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process
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