SAP18 Protein (AA 20-172) (His tag)

Catalog No. ABIN666775

Product Details

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Protein Type: Recombinant

Protein Characteristics: AA 20-172

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SAP18 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: SAP18, 20- 172 aa, Human, His-tagged, Recombinant, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 30% glycerol, 1mM DTT.

Storage: 4 °C

Target Details

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18 (SAP18 Products)

Background: SAP18, also known as Sin3A-associated protein, is component of the histone deacetylase complex that plays an important role in the regulation of eukaryotic gene expression. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. It also has been shown to play a key role in gene-specific recruitment of the HDAC complex by a number of transcription factors including Gli, GAGA, and Bicoid. Recombinant SAP18 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Sin3A-associated protein, 2HOR0202, SAP18P, SAP18, Sin3A-associated protein, 18kDa Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide p18. NCBI no.: NP_005861

Molecular Weight: 19.7 kDa (173 aa), confirmed by MALDI-TOF.