HSP90 Protein (AA 1-732) (His tag)

Catalog No. ABIN666830

Product Details

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Protein Type: Recombinant

Protein Characteristics: AA 1-732

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HSP90 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: HSP 90 (amino acids 1-732), Human, Recombinant, His-tag, E.coli

Purity: > 90 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20 mM Tris-HCl, pH 7.4, containing 100 mM NaCl

Storage: 4 °C

Target Details

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Alternative Name: HSP 90 (HSP90 Products)

Background: HSP 90 is a human heat shock protein. In response to adverse change in their environment, cell from all organisms increase the expression of a class of proteins referred to as heat shock or stress protein. The Hsp90, a highly conserved stress-induced protein, is abundantly expressed in most tissues under nonstress conditions and is required for eukaryotic cell viability. Hsp90 is primarily a cytoplasmic protein and its function remains unknown. It exists in a dimeric form and has been observed to bind to several other cellular proteins such as retro-virus kinases, steroid receptor, heme-regulated protein kinase, actin and tubulin. Recombinant human Hsp90 alpha, fused to His-tag at N-terminus, was cloned into an E. coli expression vector and was purified to apparent homogeneity by using conventional column chromatography techniques. Synonyms: HSP 86, Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, Heat shock protein 90-alpha Renal carcinoma antigen NY REN 38, D6S182, FLJ26984, FLJ31884, Heat shock 90kDa protein 1 alpha, heat shock protein 90kDa alpha (cytosolic), class A member 2, HSP84, HSP86, Hsp89, HSP89A, Hsp90, HSP90A, HSP90AA1, HSP90ALPHA, HSP90N, HSPCAL3, HSPCB, HSPN, LAP2, Lipopolysaccharide associated protein2, LPS associated protein 2, NY REN 38 antigen, hsp90, Heat shock protein HSP 90-alpha. NCBI no.: NP_005339

Molecular Weight: 86.8kDa (752aa), confirmed by MALDI-TOF.

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals