MED4 Protein (AA 1-270) (His tag)

Catalog No. ABIN666993

Product Details

Target: MED4 (Mediator Complex Subunit 4 (MED4))

Protein Type: Recombinant

Protein Characteristics: AA 1-270

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This MED4 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: MED4, 1-270aa, uman, His tag, E.coli

Purity: > 80 % by SDS - PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl

Storage: 4 °C

Target Details

Target: MED4 (Mediator Complex Subunit 4 (MED4))

Alternative Name: MED4 (MED4 Products)

Background: Mediator complex subunit 4(MED4) is also known as mediator of RNA polymerase II transcription subunit 4 or vitamin D3 receptor-interacting protein complex 36 kDa component (DRIP36). This protein is a component of the vitamin D receptor-interacting protein (DRIP) complex which functions as a nuclear receptor coactivator. The DRIP complex is capable of activating nuclear receptors in a ligand-dependent manner. Recombinant human MED4, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ARC36, DRIP36, VDRIP, Mediator complex subunit 4 Activator-recruited cofactor 36 kDa component, HSPC126, Mediator of RNA polymerase II transcription subunit 4, TRAP/SMCC/PC2 subunit p36 subunit, Vitamin D3 receptor-interacting protein complex 36 kDa component. NCBI no.: AAH05189

Molecular Weight: 30.7kDa (278aa), confirmed by MALDI-TOF

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha