K-RAS Protein (AA 1-185) (His tag)
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- Target See all K-RAS (KRAS) Proteins
- K-RAS (KRAS) (GTPase Kras (KRAS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-185
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This K-RAS protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- KRAS, 1-185aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product KRAS Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl,1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- K-RAS (KRAS) (GTPase Kras (KRAS))
- Alternative Name
- KRAS (KRAS Products)
- Target Type
- Viral Protein
- Background
- KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras,K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3,. NCBI no.: AAH13572
- Molecular Weight
- 23.2 kDa (205aa) confirmed by MALDI-TOF
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