Cullin 1 Protein (CUL1) (AA 1-410) (His tag)
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- Target See all Cullin 1 (CUL1) Proteins
- Cullin 1 (CUL1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-410
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Cullin 1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CUL1, 1-410aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CUL1 Protein
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Cullin 1 (CUL1) (AA 1-776) protein (His tag)
custom-made CUL1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cullin 1 (CUL1) (AA 1-776) protein (His tag)custom-made CUL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cullin 1 (CUL1) (AA 1-776) protein (GST tag)CUL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cullin 1 (CUL1) (AA 477-776) protein (His-IF2DI Tag)CUL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Cullin 1 (CUL1) protein (Myc-DYKDDDDK Tag)CUL1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl
- Storage
- 4 °C
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- Target
- Cullin 1 (CUL1)
- Alternative Name
- CUL1 (CUL1 Products)
- Background
- Cullin1, also known CUL1, is a core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, it serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cullin1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Recombinant human CUL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Cullin-1, CUL-1, Cullin-1, MGC149834, MGC149835. NCBI no.: NP_003583
- Molecular Weight
- 49.4 kDa (430aa) confirmed by MALDI-TOF
- Pathways
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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