HAT1 Protein (AA 20-341) (His tag)

Catalog No. ABIN7278983

Product Details

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Protein Type: Recombinant

Protein Characteristics: AA 20-341

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HAT1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Characteristics: HAT1, 20-341aa, Human, His tag, E.coli

Purity: > 90 % by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT.

Storage: 4 °C

Target Details

Target: HAT1 (Histone Acetyltransferase 1 (HAT1))

Alternative Name: HAT1 (HAT1 Products)

Background: HAT1, also known as histone acetyltransferase 1, is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Recombinant HAT1 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: KAT1, Histone acetyltransferase 1 HAT 1, Histidine aminotransferase 1, Histone acetyltransferase type B catalytic subunit. NCBI no.: NP_003633

Molecular Weight: 40.1 kDa (343aa), confirmed by MALDI-TOF.