Myosin Light Chain, phosphorylatable, Fast Skeletal Muscle (MYLPF) (AA 1-169) protein (His tag)

Details for Product No. ABIN667922
Protein Name
Protein Characteristics
AA 1-169
3
2
1
1
Origin
Human
4
1
1
1
1
1
Source
Escherichia coli (E. coli)
4
3
1
1
Protein Type
Recombinant
Purification tag / Conjugate
His tag
Application
SDS-PAGE (SDS)
Options
Characteristics MYLPF, 1-169aa, Human, His tag, E.coli
Purity > 85 % by SDS - PAGE
Protein Name
Background Myosin regulatory light chains, including MRCL3, MYLPF and MYL9, regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the actin-activated myosin ATPase activity, thereby regulating the contractile activity. MYLPF is critically important for fast and slow skeletal muscle development. Recombinant human MYLPF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Myosin regulatory light chain 2, skeletal muscle isoform, MRLC2, MYL11, Fast skeletal myosin light chain 2, MLC2B. NCBI no.: NP_037424
Molecular Weight 21.2kDa (189aa), confirmed by MALDI-TOF
Pathways Myometrial Relaxation and Contraction
Restrictions For Research Use only
Format Liquid
Concentration 0.25mg/ml (determined by Bradford assay)
Buffer Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 100mM NaCl
Storage 4 °C
Supplier Images
Image no. 1 for Myosin Light Chain, phosphorylatable, Fast Skeletal Muscle (MYLPF) (AA 1-169) protein (His tag) (ABIN667922) Myosin Light Chain, phosphorylatable, Fast Skeletal Muscle (MYLPF) (AA 1-169) protein (His tag)