GRP94 Protein (AA 22-803) (His tag)
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- Target See all GRP94 (HSP90B1) Proteins
- GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-803
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GRP94 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- HSP90B1(GRP94), 22-803aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product HSP90B1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 1mM EDTA, 0.1M NaCl, 10% glycerol,
- Storage
- 4 °C
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- Target
- GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
- Alternative Name
- HSP90B1 (GRP94) (HSP90B1 Products)
- Background
- GRP94, also known as Heat shock protein 90kDa beta, member 1 (HSP90B1), is an abundant resident endoplasmic reticulum (ER) lumenal stress protein which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. It plays an important role in maintaining protein homeostasis in the secretory pathway. Also, GRP94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. Recombinant human GRP94 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: 94 kDa glucose-regulated protein, HSP90B1, GP96, TRA1, Tumor rejection antigen 1, GRP94, 94 kDa glucose-regulated protein 94 kDa glucose regulated protein, ECGP, Endoplasmin, Endothelial cell (HBMEC) glycoprotein, Glucose regulated protein 94kDa, gp96, gp96 homolog, GRP 9, Heat shock protein 90 kDa beta member 1, Stress inducible tumor rejection antigen GP96, Tumor rejection antigen gp96. NCBI no.: NP_003290
- Molecular Weight
- 94.4 kDa (819aa)
- Pathways
- Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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