DNER Protein (AA 1-640, Extracellular Domain) (DYKDDDDK Tag)

Catalog No. ABIN6699203

Product Details

Target: DNER (delta/notch-Like EGF Repeat Containing (DNER))

Protein Type: Recombinant

Protein Characteristics: Extracellular Domain, AA 1-640

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DNER protein is labelled with DYKDDDDK Tag.

Application: SDS-PAGE (SDS)

Purpose: DNER (extracellular domain) (human) (rec.)

Cross-Reactivity: Human

Characteristics: Signal peptide and extracellular domain of human DNER (aa 1-640) are fused at the C-terminus with a FLAG®-tag.

Purity: >90 % (SDS-PAGE)

Endotoxin Level: <0.1EU/μg purified protein (LAL test).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile water.

Concentration: 0.1 mg/mL

Buffer: Contains PBS + 0.02 % CHAPS.

Handling Advice: After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: DNER (delta/notch-Like EGF Repeat Containing (DNER))

Alternative Name: DNER (DNER Products)

Background:

BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor

DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.

Molecular Weight: ~120-140kDa (SDS-PAGE)

UniProt: Q8NFT8

Pathways: Skeletal Muscle Fiber Development