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CDKL2 Protein (GST tag)

CDKL2 Origin: Human Host: Insect cells (Sf9) Recombinant >80% WB
Rockland
Catalog No. ABIN6699741
Supplier Product No.: 009-001-r67s
  • Target See all CDKL2 Proteins
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This CDKL2 protein is labelled with GST tag.
    Application
    Western Blotting (WB)
    Supplier Product No.
    009-001-r67s
    Supplier
    Rockland
    Purpose
    CDKL2 recombinant protein-GST fusion protein
    Purification
    Recombinant full-length human CDKL2 was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >80% by densitometry.
    Purity
    >80%
    Top Product
    Discover our top product CDKL2 Protein
  • Application Notes

    Western_Blot_Dilution: User Optimized

    Application_Note: CDKL2 Protein is suitable for use in Western Blot. Expect a band approximately ~ 81 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1 μg/μL
    Buffer
    CDKL2 Protein is stored in 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CDKL2 (Cyclin Dependent Kinase Like 2 (CDKL2))
    Alternative Name
    CDKL2 (CDKL2 Products)
    Background

    Synonyms: KKIAMRE, P56, Cyclin-dependent kinase-like 2, Protein kinase p56 KKIAMRE, Serine/threonine-protein kinase KKIAMRE

    Background: CDKL2 or cyclin-dependent kinase-like 2 is a member of a large family of CDC2-related serine/threonine protein kinases that is postnatally expressed in various brain regions. The extremely high CDKL2 expression in brain regions suggests that it has a role in cognition and emotion. CDKL2 transcripts increase in the deep cerebellar nuclei of the rabbit after eyeblink conditioning, a model of associative learning and memory CDKL2, also known as p56 KKIAMRE, accumulates primarily in the cytoplasm with lower levels in the nucleus (1). CDKL2 or p56, and the related protein kinase had a similar pattern of mRNA expression except in the reproductive organs. CDKL2 is expressed in several human tissues, with the highest expression in testis and kidney (2). CDKL2 Protein is ideal for investigators involved in Signaling Protein, Cellular Proteins, Cancer, Cell Cycle, and Ser/Thr Kinases research.

    NCBI Accession
    NM_003948
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