Fc epsilon RI/FCER1A Protein (AA 26-204) (Fc Tag)
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- Target See all Fc epsilon RI/FCER1A (FCER1A) Proteins
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-204
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Fc epsilon RI/FCER1A protein is labelled with Fc Tag.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FCER1A Protein
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Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) protein (Fc Tag)
FCER1A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) protein (His tag)FCER1A Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) protein (Fc Tag)FCER1A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) protein (GST tag)FCER1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) protein (His tag)FCER1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) (Active) protein (His tag)FCER1A Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
- Alternative Name
- Fc epsilon RI alpha (FCER1A Products)
- Background
- High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
- Molecular Weight
- 47.3 kDa
- NCBI Accession
- NP_001992
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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